Atherosclerosis and High Fad Diets Essay -- Health

AtherosclerosisAtherosclerosis, which is a chronic inflammatory disease amongst the arteries of the human body, mud the principal cause of cardiovascular related disease (Gets, 2011). Atherosclerosis results from a complicated relationship between different factors such as lipid metabolism, blood coagulation elements, cytokines, hemodynamic stress, and behavioral risk factors. (Singla et al., 2011) The pathogenesis of atherosclerosis involves oxidative stress, endothelial dysfunction and chronic inflammation, which are initiated in response to high plasm lipid levels, especially Low Density Lipoproteins. (Yu et al., Getz., 2011) Atherosclerosis is a assistant to the pathogenesis of myocardial and cerebral infarctions, gangrene and loss of function in the limbs, which results from an repugnant inflammatory-fibro proliferative reactions to destruction of the endothelium and smooth muscle of the arterial borders (Morenoa et al., 1992). Researches have found that salvage radicals and reactive oxygen species have been suggested to be part of this pathophysiology (Calderon et al., 2008).As atherosclerosis progresses over the decades, there seems to be lesion step-up that are mostly facilitated by cellular adhesion molecules, which are expressed on the vascular endothelium and on circulating leukocytes in reaction to inflammatory stimuli this is largely due to the recruitment of inflammatory cells from the circulation and their trans-endothelial movements. (Blankenberga et al., 2003) furthermore, there is now an agreement that atherosclerosis characterizes a conjure of heightened oxidative stress characterized by lipid and protein in the vascular wall (Singla et al., 2011). Over several decades Atherosclerotic plaque matures a... ... 2438. doi 10.1373/clinchem.2007.09736010) Bayes-Genis A, Conover CA, Schwartz RS. The insulin-like growth factor axis a review of atherosclerosis and restenosis Circ Res 200086125-130.11) Blankenhorn DH. Prevention or rever sal of atherosclerosis review of current evidence. Am J Cardiol.. 19896338H-41H12) Pearson,TA, Blair,SN, Daniels,SR, Eckel,RH, Fair,JM, Fortmann,SP, Franklin,BA, Goldstein,LB, Greenland,P, Grundy,SM, Hong,Y, Miller,NH, Lauer,RM, Ockene,IS, Sacco,RL, Sallis,JF, Jr., Smith,SC, Jr., Stone,NJ, Taubert,KA AHA Guidelines for Primary Prevention of Cardiovascular Disease and accident 2002 Update Consensus Panel Guide to Comprehensive Risk Reduction for big Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American fancy Association Science Advisory and Coordinating Committee. Circulation 106388-391, 2002